Interesting... although his explanation of TSP complexity is unfortunately incorrect (or misstated). The complexity he is describing is specifically for the naive brute force search [1] algorithm for finding the shortest path for TSP. And a 200 city TSP is quite solvable, and often times even by a mobile device like an iPhone 5 [2]! Indeed, no need for all the time in the universe -- lucky for companies like UPS who utilize TSP variants regularly.
[1] http://en.wikipedia.org/wiki/Big_O_notation#Orders_of_common...
[2] http://www.math.uwaterloo.ca/tsp/iphone/