So here (http://fewagainstmany.com/blog/python-micro-frameworks-are-a...) is a post that lists some micro-frameworks for Python, such as web.py. Many of them are similar to Sinatra for Ruby (if you are familiar with that framework) and basically allow you to create very simple web applications in a single file if that is what you desire. While these are not inherently MVC, they can be used as the underlying foundation for your very own MVC framework.
As for MVC, the other big ones for Python (other than Django) are Pylons and TurboGears. Of course there are some other very heavy weight ones as well, such as Zope and Plone, but my knowledge of these is very limited, so I'll leave them for someone else to comment on.
Finally, you can could always use the WSGI spec directly and just slap together all the other "best of bread" pieces to make your own simple framework. It's actually pretty easy to do so, and the best tutorial I've found on doing just that is on Joe Gregorio's website (http://bitworking.org/news/Why_so_many_Python_web_frameworks). Check it out, it's definitely worth running through once to at least get an idea of what other frameworks are doing under the hood.
As for MVC, the other big ones for Python (other than Django) are Pylons and TurboGears. Of course there are some other very heavy weight ones as well, such as Zope and Plone, but my knowledge of these is very limited, so I'll leave them for someone else to comment on.
Finally, you can could always use the WSGI spec directly and just slap together all the other "best of bread" pieces to make your own simple framework. It's actually pretty easy to do so, and the best tutorial I've found on doing just that is on Joe Gregorio's website (http://bitworking.org/news/Why_so_many_Python_web_frameworks). Check it out, it's definitely worth running through once to at least get an idea of what other frameworks are doing under the hood.