Just taking out Dropbox and Airbnb, the average for the rest already drops quite a bit. With Dropbox at more than $4bil [1] and Airbnb at $2.5bil [2], that leaves the remaining 283 at about $5bil total, or $17.6mil each. Taking out others like Weebly would drop it further.
No, he/she is saying that "average" is a poor metric to represent the totality of the samples. This is particularly true when you have such a high standard deviation.
By eliminating some of the biggest outliers, you're reducing the standard deviation, thus making the average metric more representative.
You'd also have to disregard the companies with very low or no value, but it seems this was already done in PG's original statement: "Of the 285 _that have_ valuations..."
It would be interesting to know what the median valuation is. Half the startups will be above it, and half below it. This would provide additional interesting details.
Obviously the average of $46 million doesn't provide a clear picture at all.