Not really. It's kind of the opposite really, because you know that he's out enjoying himself, rather than pandering to the masses. He's done his service to humanity, now let him be free.
Yes I know he's just doing whatever makes him happy but I sometimes feel sad that if the internet had come out just 10 years earlier, he may have gone the self-published route which didn't really exist at that time for him. Instead of just being limited to 10 years of his creative expression, he may have had the opportunity to pursue it on his own for as long as he wished.
Although articles about him are very tough to find, I read one interview where supposedly he does paintings and when they are done, he burns them.
I guess my comment would better be rephrased as "It's a shame that by working in a system that is solely focused on profit, it caused him much more stress and discomfort than he was prepared to take on and, as a result, felt the only sensible path for him was to disappear."
where he said "I've never regretted stopping when I did."
However, I seem to remember from his 10th anniversary book, that the main reason for stopping was all the conflict and grief from dealing with the syndicate, not the content of the work. He had even taken a sabbatical at one point near the end of the strip because the stress had been too much.
I guess I just like thinking about alternate realities. Even in a world where he self-published and had full control, it's still possible he may have discontinued the comic after 10 years. Maybe the time was just right no matter what.