Did you try using official Nvidia drivers [1] (as opposed to notebook creator supplied ones)?
I have been using Quadros for long time (multiple generations, currently on Thinkpad with Quadro 2000M) and I never had any issue with games. Both compatibility and performance wise for me Quadros have been more or less equivalent to corresponding GeForce cards.
I do however always try to use the latest drivers from Nvidia and I turned off Optimus in BIOS.
Unfortunately, since it's not my own personal hardware and I really don't need any graphics past an X terminal and Visual Studio to do my job, I'm not really willing to muck with the drivers.
My work laptop has a Quadro GPU, and I did try Starcraft 2 on it. SC2 wouldn't actually recognize the chipset, so I was set on very low settings.