I used to run sco xenix and unix binaries on linux via ibcs. That worked by registering a binfmt-something-else not -misc, because it didn't load an interpreter like qemu or wine, the kernel ran the binary directly, so the binfmt was something like -sysv or -ibcs2 or something. Not for real / production, just for fun. I got it go but no situation ever arised that wasn't better solved some other way. And good thing because I don't think that has worked for many years.