I have it on my to-do list to install FreeDOS on bare metal to set up a retro gaming box. Tried once, but for some reason the installer failed writing to disk. Anyway, if anyone is making new FreeDOS games, I'll gladly pay for them, and it'll give me an excuse to go down that avenue again.
If enabling CSM in your BIOS isn't an option or isn't enough for FreeDOS, there is a translation layer that can get it to run on UEFI hardware: https://github.com/FlyGoat/CSMWrap
OK, I just posted a comment saying FreeDOS will no longer run on hardware because of lack of BIOS support, but that might change things I guess. Hope it can be made to work.
Another big problem for FreeDOS is the lack of sound card support. I do not know if anyone has solved that yet.