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As I understand it, a human egg has about an equal quantity of nuclear and mitochondrial DNA. The mitochondrial DNA is highly replicated, though (about 100,000 mitochondria, each with ~16600 base pairs of DNA).


I was going to call BS on this one, but after crunching some numbers, if anything this is likely an underestimate.

human nuclear genome size (haploid): 3.1 billion bp

mitochondrial genome size: 16 000 bp

1 human nuclear genome per egg -> 3.1 billion bp nuclear DNA

100 000 mitochondria, each with 1-10 genomes per mitochondrion [1] -> 1.6-16 billion bp mitochondrial DNA

So the ratio of mitochondrial to nuclear DNA in human eggs is on the order of 0.5 to 5.

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC4988970/


Thank you for the tidbit that mitochondria each may have multiple copies of that genome.




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