You don't need to take that much. LD50 is surprisingly close to the normal dose, and possible to do if you don't realise that cold remedies contain it (or that aminocetophen and paracetamol are the same thing!)
The drawback of Ibuprofen is that it tends to cause damage to stomach and intestinal linings. That's why you are advised to take with food and/or lots of water. You don't want it absorbing all in one place. Long term use exacerbates the effect, making it more likely to cause ulcers and eventually internal bleeding. My partner ended up in the hospital with a serious internal bleed caused by taking Ibuprofen daily for chronic pain. I'm not saying don't use it, just be aware of the risks.
Ibuprofen is possibly worse than that, it seems that it may interfere with sex hormones. [1]
This 2017 study I found in 30s of searching is seemingly underpowered at n=30 or so, but the (preliminary) implication is awful enough that I won't give my boys ibuprofen at all. Out of abundance of caution.
They can have naproxen or acetaminophen instead -- we keep those out of reach and teach our children not to touch them without adults.
Ibuprofen is anti inflammatory which paracetamol isn't. IIRC this means ibuprofen can hide infections. I had a doctor friend who avoided its use as generic pain relief for that reason.
Again and again, this hepatologist makes his message clear: "Acetaminophen (Paracetamol) is the safest anti-fever and anti-pain medicine even among patients with liver disease. It is the first choice for fever and pain management even in advanced cirrhosis."
Look for some of his other posts on the topic for studies and citations.
