Of course. I was strictly refering to .NET preinstalled in Windows as per the comment I replied to, which I believe only applies to Framework 4.8.

Although, on re-read, maybe they meant there's a good chance another application already installed it? This I wouldn't agree with, as applications often insist on installing different versions of the system-wide runtime, even for the same major version.

It doesn't usually happen (on Windows but realistically elsewhere too) unless you publish an application as self-contained.

To be specific, .NET install is version-aware and would manage those side by side, unless the destination folder is overridden.