> in English - a word is a word, and the individual letters that it's composed of are almost always pronounced the same way

Some context-dependent examples: "read": /ɹid/ vs. /ɹɛd/; "lead": /lid/ vs. /lɛd/ (plumbum); "desert": /ˈdɛz.ɚt/ vs. /dɪˈzɝt/.