Startups do not have to worry about such issues until they themselves become incumbents, which they do after the previous incumbents were brought low by antitrust action.
Seems to have worked out okay in tech, because we have the benefit of technological progress. WinTel dominance is moot because smartphone is the name of the game, and MS was unable to execute. The Mac and Linux were also able to catch up in the meantime, even though Windows is still numerically dominant on desktop.
Which no startups have. So, antitrust favors incumbents, of course.
> money they've made operating in the competitive space cleared out
Again, not startups. It’s incumbents that take advantage of opportunities like that.