To be honest, apart from the containment systems you mentioned, much of biology basic research doesn't actually need that much sophisticated kit for basic cloning and genetic manipulation.
I think the real thing that stops it - it not that you can't make stuff that kills people, but the problem of specificity - ie how do you stop it killing yourself.
A lot of the key reagents can just be bought - and BTW it's why code like Screepy exist ( https://edinburgh-genome-foundry.github.io/ ),.
I think the real thing that stops it - it not that you can't make stuff that kills people, but the problem of specificity - ie how do you stop it killing yourself.