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It is a long way off clinical application but could potentially be useful for treatment of "in transit" metastases - e.g. multiple metastases spreading from a distal site on a limb and growing on the skin. At the moment these are usually removed surgically or treated with electrochemotherapy. Unlikely to replace conventional treatments such as immunotherapy (checkpoint inhibitors), targeted inhibitors (BRAF/MEK) or emerging treatments such as personalised mRNA vaccines.

(Lead clinician for the melanoma multidisciplinary team at a major teaching hospital in London for what it's worth)



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