Both of these have now been observed. Of course your underlying observation holds: prokaryotes nuclei are fundamentally fragile in the face of these compounds. However, my understanding is that in both cases, it appears that microscopic pathogens are capable of rapidly evolving rudimentary mechanical barriers.
Alcohol resistance: https://www.medicalnewstoday.com/articles/322646
Bleach resistance: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464077/