I think there's a good reason that trying to cheat death and meeting a grim end as a result is such a common trope in mythology. Even in ancient times I think people generally recognised the profound harm refusing to accept the inevitability of death does to a person.
We have religious mythologies promising eternal afterlife since ancient times too, I think it's more an irrational coping mechanism to deal with it's inevitability. Everybody grows old and dies, that doesn't make death less horrific, it's the worst aspect of the human condition. We just often pretend it's not in various ways to better deal with it. But that shouldn't prevent us from trying to cure it the same way we are trying to cure cancer.
