Basically, No, IMO. I do embedded systems. Most of the important differences, would be covered under the peripheral side. Assuming you move to a drastically different ARM chipset, there would be no difference.
As disappointing as it may be to some people, architecture rarely winds up mattering much (although you might be able to argue that some elements that make it into the peripherals are "architectural"). At least for software developers, there will never be a reason to dig into architecture. Maybe for some stuff interrupt, or hardware exception related.
I've found that the specific chipset and compiler tend to be more important for software developers working close to hardware. Even ASM code probably won't really matter, unless you plan to heavily rely on it; I would guess it could come into play if you plan on writing heavy ASM code, which I doubt you'd ever do on a modern architecture... maybe you're REALLY trying to save memory, or think you can improve CPU performance for some reason. Seems far fetched in almost every application, but I bet people out there are doing it for good reasons.
Of course, there may always be little places where you end up doing stuff with ASM, but again IME they tend to be where the peripherals and architecture meet.
As disappointing as it may be to some people, architecture rarely winds up mattering much (although you might be able to argue that some elements that make it into the peripherals are "architectural"). At least for software developers, there will never be a reason to dig into architecture. Maybe for some stuff interrupt, or hardware exception related.
I've found that the specific chipset and compiler tend to be more important for software developers working close to hardware. Even ASM code probably won't really matter, unless you plan to heavily rely on it; I would guess it could come into play if you plan on writing heavy ASM code, which I doubt you'd ever do on a modern architecture... maybe you're REALLY trying to save memory, or think you can improve CPU performance for some reason. Seems far fetched in almost every application, but I bet people out there are doing it for good reasons.
Of course, there may always be little places where you end up doing stuff with ASM, but again IME they tend to be where the peripherals and architecture meet.