It just won't work that well. Recently in the past few months I've been noticing more and more ads with safari style content blockers, while ublock style continue to work fine. I fear this style of 'adblock' will have similar issues.
Brave is a Chromium clone with their own built-in adblocker. Orion is a Safari / Webkit clone re-engineered to work with Ublock Origin (which is currently the best ad blocker). So on a mac or ios, Orion will be slightly better.