It is the opposite. Reality is easy because it is familiar. Our brains are tuned to it from the core. To make something truly alien is to make something you've never seen, heard, touched, smelled, nor felt before. That is incredibly difficult, has always been, and has the potential to birth whole new genres of art.
There will never be new genres or art or music. Everything has been discovered already. Like colours, they are all already known. Sure you can have a new take something or maybe discover a new subgenre, but the majority is already there. And just because a genre would have a new "name" (just a branding thing anyway) doesn't mean it's not part of some other genre already.
You can't capture psychedelic and or mystic experiences, which are very subjective anyway and yes, rooted in _reality_ or require a reference to _reality_ as they are the so far away from that.
Do you believe that there were no genres of music born in the 20th century, or that we conveniently discovered all the genres just a few decades ago? Neither of those seems reasonable to me.