The only time I use the numpad is when I'm playing Dwarf Fortress, and that too will change after the forthcoming GUI update. I've been developing software using vi and the CLI for well over 40 years; I want my desk space back so I can move my notepad and coffee cup closer.
The problem tends to be in finding commercially-made backlit clicky keyboards without a numpad.
Can I recommend ignoring the fact that keypad is.. well keypad and treat it as additional X keys to bind?
I have binds that directly open browser, Emacs, terminal and even IM so that I don't have to use mouse. Some are more macroable, e.g. I had a job where I had to retype things from images (imagine the cost effectiveness), but because I'm lazy type I made a macro under a key that would screenshot -> OCR, key next to it was opening target app.
The problem tends to be in finding commercially-made backlit clicky keyboards without a numpad.