Got a DIY one last week with pop_os setup and it's an amazing laptop to have for a reasonable price. Having used a Pixelbook for awhile, it's hard to ever go back from using a 3:2 screen, but that's exactly what you get with Framework (obviously w/ much better specs than a Pixelbook & a full Linux install).
Been using PopOS on my DIY version since last July. The battery life isn't what I hoped for (I haven't done exhaustive testing), but otherwise I've had a great experience.
I might be doing something wrong, but using integer scaling at 2x results in a UI that's a bit too big for my tastes, but if I use 1x I feel it's too small, so fractional scaling seems to be necessary for me to get the right balance. It drives an external monitor at 1920x1080, and was just looking at buying another HDMI adapter, but I haven't yet been able to determine whether or not it's capable of driving two 1920x1080 displays in addition to its internal panel. That would be my ideal setup for WFH, I think. In case it's not obvious, my vision isn't good enough for me to feel strongly about HiDPI. =)
But, to echo what others have said: this laptop is a clear winner for my use cases. I'm very pleased that they managed to nail modularity without sacrificing build quality and aesthetics.
It runs dual 4ks for me via a thunderbolt doc (and is far less error prone than my 16" MacBook which likes to crash randomly when thunderbolt is connected)
I don't use it for gaming, but there was a slight screen tear issue that can be solved in about 60 seconds. Other than that it works perfectly well with fractional scaling over 3 monitors.