I imagine this also depends on your build and physical condition. I imagine that if you're petite and/or out of shape, they might be too heavy.

I've tried Bose and Sony noise cancelling headphones and they've all given me a headache from pressure under my ears. After reading some reviews of these, I decided to give them a shot to see how they compare. So far they are a lot more comfortable for my head shape, and I haven't noticed the weight being an issue, yet.