But noscript is like some sickness and poison immunity perk while your whole campaign is set in a swamp. Trading it for some bag of holding does not feel like a good thing.
Weighing the perk "grants poison immunity" versus the perks "increased armor bonus, durability, and resistances" is indeed the crux of the problem. When is the general improvement in quality of life from replacing armor so great that it outweighs temporarily losing immunity?
