My prediction is most of these predictions will not come true as stated, but things that have not been discovered or are not obvious will dominate change. Having seen 4 decades now since I started I have seen so many technologies and changes appear that no one even thought of at the start of each decade. It might be different this time because the internet is so prevalent today and it's much more difficult to make something under the radar.
I know this is like a hindsight 20/20 thing, but it would seem to me the only 'problems' left to solve are just the really hard ones (even on the scale of a decade): fusion, unified field theory, intelligent / extraterrestrial life, becoming multi-planetary species, etc.
My feeling is that biotech or nanotech have the most room for something revolutionary or unforseen to be produced
