Yeah, that's a good starting point. Maybe not just cryptocurrency users, but "people who have expensive digital assets on a computer that runs untrusted code".
Although, it kind of seems like, the more expensive you digital assets, the more you just need to a) hire a full time security person and b) insure your asset.
I'm not sure how a new OS would fit into that.
It seems like it would have to be people WITHOUT a lot of assets who would be the initial customers. People who can't just pay a security person to go over their images.
So maybe casual crypto users.
But wouldn't they be better off just with a custom dongle? A dongle isn't running untrusted software.
Also, isn't part of this technology that it squeezes a little more performance out of a machine without leaking information?
That takes me to the comment below... cloud hosting platforms.
(Although they tend to be very bad at threat modelling)