The 2nd-6th amendment have not exactly been effective at protecting the human rights they affirm at the state and city level. Where I live I have to get permission from the government (good luck if you're not white) to own the tools to defend myself from physical harm and the government can stop me and seize my property on a whim.

I believe we need more defense in depth. We need our human rights to be protected by every level of government and informally by society itself.