I just set mine to Quito, Ecuador (anywhere on the equator will do). That keeps things relatively consistent throughout the year, instead of following sunset/sunrise times which have no bearing on my sleep/wake schedule.
I think the gist isn't to match the outside so much as to set a pattern of turning on F.lux at the same time every day, to settle into a night-time routine.
I know the reasoning, I guess I'd just prefer to set it manually based on when I'm actually using my machine. As in, near the end of my usage at night I want it to be very orange no matter what the time is.