I've listened to Sam Harris' stuff too not long ago and I'm not sure if it changed my life, but it definitely blew my mind and is part of a broader interest in this type of stuff that is changing my life. I don't agree with all his opinions, but his interview with Tim Ferriss and his book Waking Up are both fantastic.
Harris was initially my least favorite of the Four Horsemen -- Richard Dawkins, Christopher Hitchens, Sam Harris, and Daniel Dennett -- but my opinion has completely changed over the last year. With Hitchens gone, he's playing the role of public intellectual better than anybody else I'm aware of right now. I highly recommend his podcast.
I was able to make it through about half of that before the irrelevant mewling about "privileged powerful male elites in U.S. society" became too much for me.
If anybody is interested in what Harris actually had to say, they should go read it for themselves:
Tim Ferriss Interview: http://fourhourworkweek.com/2014/06/18/sam-harris/
Waking Up (narrated by Sam himself, which I prefer): http://www.audible.com/pd/Religion-Spirituality/Waking-Up-Au...