WhatsApp is that middle ground in some parts of the world.
Upon moving to Europe we discovered that WhatsApp is the preferred way to connect with friends, employees, social groups and schools. It was actually the driving factor in me conceding and setting up a FB account.
I think they may be correlating it with the similar sounding word “hurl”. Huel on the other hand is readily available in shops in pre-made form, and I’ve seen it in vending machines in Heathrow.
The article paints hookworms as disease causing parasites, responsible for the poor health and economic circumstances in the South.
But this year hookworms were involved in a clinical trial on type 2 diabetes and cardiovascular disease with positive results, so maybe the south were onto something.
There have been many such studies using hookworms to investigate whether aspects of out physiology can benefit from parasites, whether our bodies have evolved to expect them to the point that living without is unnatural. BUT, my understanding is that these studies have always used only male or only female worms. The patient is "infected" with a very limited number and they will all eventually die. That is very different than being infested with a colony's worth of worms. And, most importantly, any released eggs will not ever go on to infect other people.
These worms are also easily eradicated from the body if needed. Ivermectin cannot kill covid, but it murders worms very well.
Aside but my favorite ivermectin study was the meta study that found that there was a relationship between whether or not ivermectin improved Covid outcomes and the rates of endemic parasites that could be treated with ivermectin.
So, people who got the dewormer did better - but only in those places where people had a lot of parasitic worms. The obvious implication being they did better because they had a parasitic worm infection which was incidentally treated with ivermectin.
There was also an in vitro study that showed ivermectin killed SARS-CoV-2 viral particles. Of course the conspiracy theorists left out dose information, which would be so high that it would just kill you outright.
So the truth behind the two halves of the ivermectin conspiracy were basically: if you have parasites, getting rid of them will help your COVID prognosis; and if you don't mind being dead first, we can prevent COVID from killing you.
The study did not show that Ivermectin killed SARS-CoV-2 viral particles. Prior to the pandemic, Ivermectin was known to act as an broad anti-viral. This is due to Ivermectin being a protease inhibitor, i.e. it blocks an enzyme from acting. It's important to note that this is the mechanism through which approved anti-virals for SARS-CoV-2, such as Paxlovid, operate.
There are also some studies indicating that it can shrink certain tumors. My assumption was that it just stirred up the immune system in general, un thevsame way that a flu shot can decrease the severity of a cold.
It would be nice if every comment was fully cited, but would probably be counter-productive since most people don’t have the time to find citations.
Until everyone’s knowledge is represented in some kind of knowledge graph, simply finding a citation “of that paper I read last year” can be a lot of work. So for now, it’s more effective to talk generally and cite a paper when it is relevant (when discussing methods etc).
I don’t know if you’ve done an in vitro study before, but I have. I can make anything kill anything in Petri dish. Heck I can make anything kill anything even in a mouse. If ANYONE can figure out how to reliably correlate preclinical studies (that’s the technical term for any study not done in humans) to human outcomes, they’d be a literal trillionaire in a decade. But that’s not possible yet.
Ivermectin did not work. It never did. People in the initial waves off were dying of Covid because their own immune system killed their lung. Ivermectin did jackshit about it. Multiple clinical trials proved that. So it’s time to hang that hat and find the next favorite conspiracy theory.
During covid you would often read that medicine X or Y would work on some people or in some country.
I always wonder if those didnt work because people often have more than one infection ongoing. And obviously two or more infections are more deadly, since your organism is fighting not only coronavirus but something else as well. So I wondered if the medicines didnt defend against that something else.
Dewormer in USA, some anti flu medicine in Italy and other in Poland...
Ah that makes more sense. I recall one of the studies saying that the worms couldn't reproduce, whereas the article on HN mentions millions of eggs causing an infestation.
If anyone is interested in controlling parasites by playing with their reproduction, consider the "screwworm fence" down in Panama. Irradiated male screwworm flies are bred and released en masse, to mate with wild females to produce nonviable offspring and thereby halt the species spreading further north. It works so well that few have heard about it.
I'm not an Apple device user so I could be mistaken, but Apple devices must be collecting all of this information about their users if Facebook is able to access it.
Out of curiosity, how do you use Node for this purpose? Is it building a real time dashboard?
My company has possibly similar challenges. We have lots of sensors on equipment that streams information every few ms through a time series database from the vendor. It's used to build monitoring dashboards, trigger alarms and help engineers to prioritize and optimize equipment settings, and look for trends over time.
It's such high volumes that capturing it and analyzing can be difficult, so we use a combination of vendor systems, Azure Synapse and Power BI.
There are still lots of opportunities to improve, and I'd be interested to hear how you landed on your setup and what you do with the data.
It’s mainly for data transformation and transport. Solar inverters don’t deliver data in the same formats, there are no protocols and apparently most engineers in the solar panel business still think FTP (not SFTP) is fine but some will deliver a file per reading while others will aggregate and so on.
We use node to gather the data and transform it into consumptive formats that our 3rd party AI vendor can work with, as well as store it in a range of SQL databases for our own PowerBI consumption. We do no frontend work.
We don’t use node because it’s a good idea to use node for this. We use node because we try to use TypeScript as much as possible because we’re a small team and having a single language covering as much of our stack as possible makes it easier to work together.
That actually sounds like a really funny feature that would make the brand be mentioned in headlines worldwide. I hope someone at a phone company in Mumbai also has this idea and makes it as an add-on to your USB-C port or something so we can all have this :D
If his fee is based on profits, he needs to be correct some of the time. The types of events you mentioned aren't all hype and he can't will them into existence, so maybe he's on to something?
No idea about his specific fund's pricing but the "traditional" pricing model for hedge funds is 2 and 20, ie, 2% of assets under management plus 20% of profits.
But also, a performance fee is kind of like an option in that it has an asymmetrical payoff - if you make 100 in profit, you get 20, but if you lose 100, you don't have to pay 20. All other things being equal, the expected value of a performance fee will increase with portfolio size as long as there is a chance you are right (and there is always a chance you are right).
Yes, the predicted events will have to come to pass eventually to collect on the performance fee. Nobody (not even this guy) knows when that will happen, but everyone knows that it will happen eventually, and in the meantime, you can position yourself so as to maximise the payoff when they do.
I believe most hedge funds also charge a fee on total assets under management regardless of profitability, so he’d be profiting just by luring in new customers, profits not necessary.
>If his fee is based on profits, he needs to be correct some of the time. The types of events you mentioned aren't all hype and he can't will them into existence, so maybe he's on to somethin
So all he's doing is timing the market. That's it. And here's the thing: it's impossible. Statistically, he and everyone else are on average bad at it. For example, over the past year he and many folk have predicted recessions, depression, stagflation and even collapse. And here in the US they've been entirely wrong. And if you invested according to them then you lost a lot of money.
The reason why this is a bad investment is because the opportunity cost of what you could be doing with your money during all the time that he's wrong up until he's right. And then you have to hope that when he's right, it makes up for all the time he was wrong. Statistically, it's unlikely.
Your best bet is to make the best investment you can that pays today, not a bet on a payday that could happen tomorrow... Time in the market beats timing the market.
