I’ve used both. I would say nextflow is a more production-oriented tool. Check out seqera platform to see if any of the features there seem useful. It can also be useful to get out of the wildcards/files mindset for certain workflows. Nextflow chucks the results of a step into a hashed folder, so you don’t have to worry about unique output names.

That said, I do find snakemake easier to prototype with. And it also has plenty of production features (containers, cloud, etc). For many use cases, they’re functionally equivalent